This chapter on public health genomics examines three examples of projects facing such challenges, in order to anticipate the ethical and policy issues that public health uses of research biobanks raise for those responsible for their design and governance. The chapter looks at issues of informed consent, return of results, and community engagement. Public health ethics differs from traditional biomedical ethics in many respects, specifically in its emphasis on societal considerations of prevention, equity, and population-level issues. Health care systems are increasingly faced with the need to integrate clinical medicine with public health and health policy.In Ashcroft RE Dawson A Draper H McMillan J, Principles of Health Care Ethics. London: John Wiley & Sons, 2007, pp. 563-568. Wikler, D. and Cash, R. "Ethical Issues in Global Public Health" In Robert Beaglehole and Ruth Bonita, eds. Global Public Health: A New Era, Second Edition, Oxford University Press, 2009; Wikler, D.•Another ethical dilemma that can be troublesome for nurses is balancing empirical knowledge that a nurse knows is a fact versus a patient’s personal or religious beliefs. Many religious beliefs prevent people from having certain medical procedures done. Sometimes, these same procedures could be life saving for a patient.